Which of the following labs are included in a Quad screen?

Study for the ABOG Oral Boards Obstetrics Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

The Quad screen is a maternal blood test that assesses the risk of certain fetal anomalies, including Down syndrome and neural tube defects, typically performed during the second trimester. The components of the Quad screen include Alpha-fetoprotein (AFP), unconjugated Estriol (E3), human Chorionic Gonadotropin (HCG), and Inhibin A.

Alpha-fetoprotein is a protein produced by the fetal liver, and its levels can indicate risks for conditions such as spina bifida and other neural tube defects. Unconjugated Estriol is an estrogen produced by the placenta and fetal adrenal glands, and its levels can assist in assessing fetal wellbeing. Human Chorionic Gonadotropin is a hormone produced during pregnancy, and its levels are useful in screening for Down syndrome. Inhibin A is produced by the placenta and can also help determine risks for chromosomal anomalies.

The inclusion of these specific markers provides a comprehensive profile that allows clinicians to evaluate the risk of certain genetic conditions. The other listed options include incorrect combinations of hormones and markers not typically used in the Quad screen protocol. By focusing on these four analytes, the Quad screen is designed to give an effective assessment of the likelihood of certain fetal conditions.

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