ABOG Oral Boards Obstetrics Practice Test

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What is the recommended starting dosage for levothyroxine in a new patient?

0.5-1 microgram/kg/day

1-1.5 microgram/kg/day

1-2 microgram/kg/day

The recommended starting dosage for levothyroxine in a new patient is typically set at 1-2 micrograms per kilogram of body weight per day. This dosage range is supported by clinical guidelines and is based on various factors, including the patient's age, weight, and the severity of hypothyroidism.

Starting in this range allows for adequate adjustment and monitoring of thyroid hormone levels, ensuring that the desired therapeutic effects are achieved without the risk of overtreatment. Additionally, this careful dosing approach helps safeguard against potential side effects associated with too much thyroid hormone, such as cardiac issues or osteoporosis.

In cases of mild hypothyroidism or in older adults, a more conservative approach with lower dosages may be advisable, which aligns with the potential variations in individual metabolism and responsiveness to the medication. Overall, the 1-2 micrograms per kilogram range provides a solid foundation for optimal management of hypothyroidism while allowing for tailored adjustments based on subsequent lab results and clinical response.

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2-2.5 microgram/kg/day

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