What is the typical survival rate for fetuses with isolated congenital diaphragmatic hernia born at a tertiary care center?

The typical survival rate for fetuses with isolated congenital diaphragmatic hernia (CDH) when delivered at a tertiary care center is generally reported to be between 60-80%. This range reflects advancements in prenatal diagnosis, perinatal management, and postnatal care strategies that have significantly improved outcomes for these infants.

In tertiary care centers, which are equipped with specialized neonatal care services, timely interventions can be offered. These interventions might include prenatal counseling, delivery in a facility with a neonatal intensive care unit (NICU), and the ability to provide immediate resuscitation and surgical intervention following birth. The isolated nature of the CDH, without additional significant anomalies, further enhances survival prospects since isolated cases tend to have a better prognosis.

Research shows that while the overall survival rate can vary based on specific factors such as the size of the hernia, associated anomalies, and the gestational age at diagnosis, the 60-80% range reflects a realistic and evidence-based expectation for the outcomes of these infants when delivered in optimal care settings.