What is the most common chromosomal abnormality seen in spontaneous abortions?

The most common chromosomal abnormality associated with spontaneous abortions is actually not Turner's Syndrome but rather is a different abnormality, specifically those resulting from aneuploidy. Among the commonly seen chromosomal abnormalities in spontaneous abortions, aneuploidies such as trisomy 16, which is often not viable, are paramount.

Turner syndrome, characterized by the presence of a single X chromosome in females (45,X), can result in miscarriage but it is not the most prevalent finding in the context of miscarriages overall. This condition affects around 1 in every 2,500 live female births and is not frequently seen in the early fetal loss population.

In contrast, other conditions such as Down syndrome (trisomy 21), Edward syndrome (trisomy 18), and Patau syndrome (trisomy 13) do lead to successful pregnancies sometimes, although they may also result in miscarriage. However, it is the broad category of chromosomal abnormalities due to numerical abnormalities, particularly trisomies, that are more common in spontaneous abortions.

In reviewing this topic, it is essential to understand that while Turner syndrome has its own implications and associations, including contributing to fetal losses, it does not reflect the most common chromosomal issue encountered in