What is the main effect of myasthenia gravis on the uterus during labor?

In myasthenia gravis, a neuromuscular disorder characterized by weakness in the voluntary muscles, the primary involvement is with the neuromuscular junction where acetylcholine signaling is compromised, leading to muscle fatigue and weakness. However, the uterus is primarily driven by autonomic control and does not rely on the same neuromuscular pathways that are affected by myasthenia gravis.

During labor, the uterine contractions are regulated by hormones such as oxytocin and prostaglandins, and while myasthenia gravis affects skeletal muscles, it does not have a direct impact on the smooth muscle of the uterus. As such, the uterus typically responds normally to the physiological processes of labor, which highlights that it remains unaffected by the condition. This understanding supports the idea that myasthenia gravis does not impair uterine function during labor.