Which condition is indicated by a negative fetal fibronectin (FFN) result?

A negative fetal fibronectin (FFN) result is significant in the context of preterm labor assessment. FFN is a protein produced by the fetal membranes, and its presence in cervical or vaginal secretions can indicate that there is a risk of preterm birth within the next two weeks. Conversely, a negative FFN test indicates a low likelihood of impending labor.

When the result is negative, it is associated with a less than 5% chance of giving birth within the next two weeks, which provides reassurance to the healthcare provider and the patient. This low probability can guide management decisions regarding treatment and monitoring, often allowing for the avoidance of unnecessary interventions or hospital admissions.

The interpretation of a negative FFN result is crucial for managing patients at risk of preterm labor, as it can significantly influence care pathways and anxiety levels for expectant mothers.